Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
نویسندگان
چکیده
منابع مشابه
Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
Methylation of CpG islands associated with genes can affect the expression of the proximal gene, and methylation of non-associated CpG islands correlates to genomic instability. This epigenetic modification has been shown to be important in many pathologies, from development and disease to cancer. We report the development of a novel high-resolution microarray that detects the methylation statu...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2009
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkp413